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Chemical Engineering

 

Bioengineering and Advanced Functional Materials Laboratory

Y Doc. Ing. Miroslav Šoóš, Ph.D.
b miroslav.soos@vscht.cz
e +420 220 44 3251

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Laboratory led by Assoc Prof. Miroslav Šoóš was established in January 2015 at the Department of Chemical Engineering at ICT Prague. Combining engineering concepts with material science knowledge the group is currently covering several emerging areas in biomedicine, bioseparations and biotechnology (i.e. systems for combined drug delivery and imaging, scaffold synthesis and tissue engineering, quantification of cells interaction with various substrates, synthesis of multifunctional porous materials with tunable porosity and pore size distribution, optimization of monoclonal antibody production by mammalian cells etc.).

From the experimental point of view our common starting point is a preparation of building blocks such as nano- and micro-particles of various kind and bearing various surface functionalities. Such particles are consequently used to construct hierarchical structures employing self- or controlled assembly resulting in monolith or particle-like formulations. Additional surface chemistry is used to tune final properties of these materials. In parallel to synthesis of advanced functional materials for chemical applications same concepts are used to prepare materials suitable in biomedicine and tissue engineering.

In parallel to experimental activity group is very active in the field of mathematical modeling of underlying mechanisms such as colloidal stability, nanoparticle aggregation including formation of porous structure, breakup of formed clusters and modeling of transport phenomena in porous media. In the area of biotechnology focus is on the description of cell behavior under various environmental conditions including bioreactor characterization, modeling of cell growth, metabolism as well as productivity and quality of the synthesized product.

 

Laboratory of heterogeneous catalytic reactors

Y Doc. Ing. Petr Kočí, Ph.D.
b petr.koci@vscht.cz
e +420 220 443 293

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Mathematical modeling and experimental studies of catalytic reactors with emphasis on automotive exhaust gas aftertreatment and air pollution control. Reaction mechanisms and kinetics of heterogeneous catalytic reactions for abatement of toxic components in the exhaust gas (NOx reduction, and CO, hydrocarbons and particulate matter oxidation). Preparation, testing and optimization of porous catalytic layers with defined micro- and nano-structure, including imaging and 3D reconstruction of the samples. Multi-scale mathematical modeling of transport and reaction, simulations from nano-scale to the entire catalytic ractor, and software development for industrial applications.

 

Chemical robotics laboratory

Y Prof. Ing. František Štěpánek, Ph.D.

b Frantisek.Stepanek@vscht.cz

e +42022044 3236

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Our research is focused on the design and synthesis of structured particles and particle systems in two main areas – in “traditional” Particle Technology (granulation, spray drying, encapsulation, fluid bed processing, dissolution) and in the emerging field of Chemical Robotics. Our aim is to conceive microscopic chemical robots that mimic single-cell organisms in that they are capable of autonomous movement (chemotaxis), they have the ability to store, chemically process and release molecules on demand, and they can recognize the target by specific adhesion. Unlike living organism, they cannot evolve or self-replicate, but they can be remotely controlled – thus the name “robots”. Further we focus on Pharmaceutical Engineering, where our aim is namely to understand the process-structure-property relationships for solid dosage forms such as tablets, and to use this understanding for the rational design of new products and manufacturing processes. The engineering of pharmaceutical products and associated manufacturing processes poses a challenge for chemical engineering due to the complex nature of the materials, both in terms of physico-chemical properties (e.g. amorphs, far-form-equilibrium mixtures, etc.) and in terms of process equipment and scale-up (e.g. multiphase and solids flow). Examples of our projects include the use of naturally sourced particles as drug carriers (yeast glucan particles), development of nano-structured carriers for cancer theranostics, use of 3D printing for the manufacture of personalised medicines, and the development of new approaches in the fight against antibiotic-resistant bacteria. We also develop new computer simulation tools of particle-based processes.

 

Laboratory of microchemical and biochemical engineering

Y Prof. Ing. Pavel Hasal, CSc.
b hasalp@vscht.cz
e +420 22044 4446

Members of this horde deal with several highly attractive scientific areas, always under the supervision of a leading expert in that field:

prof. Pavel Hasal – bioreactors with immobilized fungi for the treatment of waste water, biological fuel cells

prof. Dalimil Šnita – membrane separation processes driven by electric field, mathematical modeling of multiphysical systems, fabrication of microfluidic chips

prof. Michal Přibyl – microbioreactors with slug flow, liquid addressing in microfluidic systems, mechanisms of electrochemical and electrokinetic processes, chemical signal transmission in cellular populations

prof. Zdeněk Slouka – microfluidic biosensors, Lab-on-a-Chip devices, microsystems for total analysis (mTAS), techniques for the fabrication of microfluidic devices

Other group members: Dr. Jiří Lindner, Dr. Lucie Vobecká, Ing. Pavel Beránek, Ing. Rudolf Flittner, and a student band. The scientific team has three well-equipped laboratories including powerful computers. Three scientific projects supported by the grants of Czech Science Foundation and Ministry of Education of the Czech Republic are currently solved in the group. The team members collaborate with excellent foreign institutes (Princeton University, University of Notre Dame, Technische Universiteit Eindhoven), other Czech scientific teams and partners from industry.

 

Fire safety engineering

Y Doc. Dr. Ing. Milan Jahoda
b Milan.Jahoda@vscht.cz
e +420220 443 223

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The main aim of the Laboratory of Fire Engineering is the active use of methods of computational fluid dynamics (CFD) in resolving the problems of burning, fires spreading and extinguishing of fires. Areas related to the dynamics of combustion are also studied, for example the kinetics of thermal decomposition of solids, the rate of evaporation of volatile liquids during combustion, rate of spread of flammable gas leakage from storage tanks. For calculations the special CFD programs are used (Fire Dynamics Simulator (FDS), FireFOAM and ANSYS Fluent). Computational methods are complemented by experiments in laboratory-scale. The research group collaborates with the Technical Institute of Fire Protection in Prague on research projects and implementation of large-scale fire tests.

 

Process and System Engineering

Y Doc. Dr. Ing. Tomáš Moucha
b tomas.moucha@vscht.cz
e +420 220 443 299

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In the group, apart from basic research and pedagogic activities, large attention is devoted to industrial research. Present day issues of industrial process units are approached via process simulation or direct experiments. Our interest is focussed on gas (or vapour) - liquid mass transfer processes. In this field, our group has rich experience and extensive database of our own experimental data. Apparatuses of laboratory and pilot-scale are at disposal. Apparatuses available for the fundamental research include apparatuses for studying of mass transfer mechanisms (processes at the interface) such as agitated tank with calm liquid surface, agitated tank with gas-liquid dispersion, wetted wall column and other necessary equipment, which help determining equilibrium and kinetic data for reliable design of industrial columns even for systems with not well defined physical properties. For the industrial research, available apparatuses include an absorption column up to 0.4m in diameter, multiphase agitated tanks up to 0.6 m in diameter, bubble column with ejector gas distributor with 0.4 m in diameter and distillation column of 0.4 m diameter.

Updated: 19.11.2016 17:14, Author: fchi

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